Veterinary drug “Amprokoxide”
Annotation

Trade name:
Amprokoxide

AMPROCOXIDE

Drug form:
Oral powder

Description:
White powder

Composition:
1 g of powder contains
Active substance: Amprolium hydrochloride 250 mg
Sulfaquinoxaline 250 mg
Menadione (vitamin K3) 5 mg

Pharmacological group:
Coccidiostatic agent

ATC vet code:

QP51BX52 – Amprolium, combinations

Pharmacological action:
Amprolium hydrochloride is a coccidiostatic agent that is active against protozoa of the order Eimeria, especially against Eimeria tenella, Eimeria acervulina and Eimeria necatrix. Sulfaquinoxaline is a chemotherapeutic agent that has a bacteriostatic effect on many gram-positive and gram-negative bacteria, and also has a coccidiostatic effect on protozoa of the order Eimeria (Eimeria acervulina, Eimeria necatrix, Eimeria maxima, Eimeria brunetti). Vitamin K3 helps reduce bleeding in the small intestine and cecum.
The coccidiostatic effect of amprolium hydrochloride is due to its chemical structural similarity with thiamine (vitamin B1), which is essential for the viability of coccidia. Since amprolium hydrochloride has better penetration than thiamine, it easily penetrates the parasite cell and takes an important place in its metabolism, resulting in a violation of carbohydrate metabolism and the death of coccidia.
The structure of the cell membrane of the intestinal mucosa of poultry and animals is almost impermeable to amprolium hydrochloride, which makes the drug non-toxic when used in therapeutic doses. The main part of amprolium hydrochloride (up to 97%) is excreted from the body with feces.
The drug is compatible with vitamins and food additives used in poultry and livestock.

Indications:
Amprolium is used for the treatment of all types of coccidiosis: in calves, sheep, goats and poultry, and for prophylactic purposes in poultry.

Method of administration and dosage:
The drug is administered to the target species orally.
Calves, sheep, goats - 1 g of the drug per 10 kg of live weight, for 5 days, with drinking water.
Poultry - 10 g of the drug is dissolved in 20 l of drinking water, the duration of treatment is 5 - 7 days.
For the purpose of prophylaxis in poultry - 10 g of the drug is dissolved in 40 l of drinking water, the duration of treatment is 3 - 4 days.

Side effects:
When using the drug in large doses, egg laying, as well as growth and development, may decrease.

Contraindications:
Hypersensitivity to amprolium hydrochloride, sulfaquinoxaline and other substances in the composition.

Do not use in cases of impaired kidney and/or liver function.

Withdrawal period:

Meat 14 days
Eggs 10 days

Storage conditions:
Store in a dry, dark place, out of reach of children, at room temperature

Product form:
500 g of powder placed in a laminated foil package

Shelf life:
3 years.

Country of manufacture:
Georgia

Manufacturing company:
LLC "Davati"
Tbilisi, Gr. Khandzteli St. No. 10.