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EQS-5 T
Instructions for Use
A product for regulating sexual functions in cats and dogs

General Information

EQS-5 T is a product intended for regulating sexual functions (heat/estrus) in cats and dogs.

Active ingredient: synthetic progestagen megestrol acetate (17-alpha-acetoxy-6-methyl-pregna-4,6-diene-3,20-dione).

Each EQS-5 T tablet contains 5 mg of megestrol acetate.

The product is available in packs of 10 tablets in blister or non-blister packaging, in vials, or in medical glass containers with plastic caps, as well as polymer or glass bottles and jars with plastic lids.

Store with caution (List B) in a dry place protected from light at a temperature of 5°–25°C. Shelf life is 3 years from the production date if storage conditions are observed.

Pharmacological Properties

The active ingredient of EQS-5 T, megestrol acetate, has progestogenic activity as well as significant anti-estrogenic and antiglucocorticoid effects.

Method of Administration

EQS-5 T is used in female dogs and cats to suppress heat, and in male dogs and cats to reduce sexual activity and regulate undesirable behavior such as aggression, attraction to marked places, tendency to roam, and increased excitability.

EQS-5 T is recommended for cats and small dogs, while EQS-20 T is recommended for large dogs.

The product is administered orally, preferably under the tongue or together with a small amount of delicacy/food, 1–2 hours before feeding.

Use in Cats

In cats, EQS-5 T is used. The dosage depends on the animal’s sex and the purpose of administration.

To Delay Heat in Cats

Administer between heat periods:

• 1 tablet once every two weeks, or

• 0.5 tablet once every week.

The duration of treatment should not exceed 18 months. A new course may begin only after the normal physiological cycle (heat) is restored.

To Stop Heat in Cats

Administer 1 tablet daily for 5–7 days, starting no later than 3 days after the onset of heat, until the signs of heat disappear.

It is recommended not to interrupt heat more than twice a year.

If it is difficult to determine whether heat has already started, delaying heat is preferable to stopping it.

To Reduce Sexual Activity and Undesirable Behavior in Cats

Administer EQS-5 T:

• 1 tablet once daily for 5–7 days,

• then once weekly.

To Delay Heat in Female Dogs

Administer 0.5 mg of megestrol acetate per kg of body weight daily, 7–15 days before the expected onset of heat.

The duration of administration depends on the desired delay period but should not exceed 32 days.

Heat may begin several days after discontinuation of the product.

After prolonged administration (approximately 1 month), heat usually begins after 4–6 months, sometimes after 2–9 months.

No more than 2 treatment courses per year are recommended.

EQS-5 T / EQS-20 T Dosage for Delaying Heat in Female Dogs

To Stop Heat in Female Dogs

Administer 2 mg of megestrol acetate per kg of body weight daily at the first signs of heat (bloody discharge), but no later than 3 days after the onset of heat.

During the first 3 days, administer the full daily dose; during the next 3 days, administer half the daily dose.

After discontinuation of the product, heat usually begins after 4–6 months, sometimes after 2–9 months.

No more than 2 treatment courses per year are recommended.

EQS-5 T Dosage for Stopping Heat in Female Dogs

Use in Male Dogs

To reduce sexual activity and regulate undesirable behavior (aggression, attraction to marked places, tendency to roam, increased excitability), administer 2 mg of megestrol acetate per kg of body weight for one week.

After the desired effect is achieved, continue with half the dose for 2 weeks.