Trade name
Piperazin
Form of the drug
Oral tablet
Description
White, round tablets with a flat surface, without a shell. With a dividing mark on one side, with the manufacturer's logo on the other side
Generic (international non-proprietary) name
Piperazine adipinate
Composition
One tablet contains
Active substance: piperazine adipinate 500 mg
Pharmacological group
Anthelmintic.
Pharmacological action and pharmacokinetics
The drug belongs to the anthelmintic. The pronounced effect is characteristic of adult and immature helminths, causes muscle paralysis of nematodes and disrupts the function of their nervous and muscular systems. The degree of dehelminthization when using the drug is 95%, and with repeated use - 100%.
The drug is rapidly adsorbed (absorbed) into the tissues and biological fluids of the animal's body, is well distributed, creating a high concentration in the blood plasma. As for the excretion of the drug, it is mainly produced by the kidneys with urine.
Indications
Piperazine is used for the treatment of ascariasis, paraascariasis, neascariasis, heteroacidosis, echinuriasis and toxocariasis in the following animals and birds: cattle, including calves, goats, pigs, horses, dogs, cats, quail, geese, chickens, ducks.
Method of administration and dosage:
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Animal species
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Dose
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Duration of treatment
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Cattle. Including calves
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0.7 g (1.5 tablets) per kg of live weight,(maximum daily dose 160 g)
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Single dose
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Pigs and goats
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0.7 g (1.5 tablets) per kg of live weight
(maximum daily dose 15 g)
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In the morning for 2 days. If necessary, the course of treatment can be repeated after 2 months.
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Horses
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0.7 g (1.5 tablets) per kg of live weight
For adult horses
Maximum daily dose 80 g
For 1-2 year old horses maximum daily dose 60 g
For younger horses maximum daily dose 30 g
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2 days. After 10 weeks, the course can be repeated
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Cats and dogs
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0.5 g (1 tablet) per 1 kg of live weight
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Single dose. The course can be repeated after 21 days
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Geese
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1 g (2 tablets) per 1 kg of live weight
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2 days.
Also, according to one of the schemes, a daily break is made between these days or the drug is given for 3 days in a row
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Chickens
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0.25 g (0.5 tablets) per 1 kg of live weight.
In chicks (2-3 months old) - 0.3 g - 0.5 g (3/4 - 1 tablet)
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Ducks
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0.25 g - 1 g (0.5 - 2 tablets) per 1 kg of live weight.
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The drug is given in the evening with water, at this time it is forbidden to drink other drinking water
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Rabbits
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0.5 g (1 tablet) per 1 kg of live weight for adults.
0.2 g (0.4 tablets) per 1 kg of live weight for young animals
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2 days. Before taking the drug, the animal is not fed for 18-24 hours.
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Withdrawal period:
Meat - 4 days
Milk - 2 days
Eggs - 2 days
Contraindications
The use of piperazine is prohibited in animals with chronic liver and kidney diseases, and also in cases of impaired gastrointestinal motility.
Side effects
The use of piperazine in therapeutic doses is not characterized by side effects, it is easily tolerated by all the above-mentioned animals and birds. However, vomiting, diarrhea, tremors may rarely occur.
Overdose
11.4 g/kg is the lethal dose of piperazine. Overdose in cats and dogs after 24 hours can cause the following signs of intoxication: vomiting, weakness, respiratory failure, tremor of the hind limbs, hypersalivation, dehydration, decreased vision. In case of overdose, it is necessary to carry out anti-intoxication measures, the use of charcoal or other enterosorbents is recommended.
Release form
10 tablets per blister, blister No. 15 in a cardboard box.
Storage conditions
Store in a dry, dark place, out of reach of children, at room temperature.
Shelf life
5 years
Manufacturing country
Georgia
Manufacturing company
LLC "Davati"
Tbilisi, Gr. Khandzteli St. No. 10.
