Veterinary drug "Daxofen 900"

Davati, Georgia

Trade name:

Daxofen 900

DAXOFEN 900

Drug form:

1500 mg oral tablet

Description:

Round tablets of yellow color with a flat surface, without a shell. On one side with a divider, on the other side with the manufacturer's logo

Generic (international non-patented) name:

Oxfendazole, Oxyclozanide

Composition:

One tablet contains

Active substance: oxfendazole 450 mg

Oxyclozanide 450 mg

Pharmacological group:

an anthelmintic agent.

ATC vet code: QP52AC52 – oxfendazole combinations

Pharmacological action:

Oxfendazole is a derivative of benzimidazole carbamate, characterized by a wide spectrum of activity. Like other benzimidazoles, oxfendazole is characterized by inhibition of the energy metabolism of parasites by blocking the action of the enzyme fumarate reductase. Blocking of adenosine triphosphoric acid hydrolyzation leads to interruption of energy supply, which in turn causes death of helminths and expulsion from the body.

Oxyclozanide is an anthelmintic agent of the salicylamide group, effective against immature and adult parasitic forms. The mechanism of action of oxyclozanide is based on the disruption of the oxidative phosphorylation cycle and reduction of the ATP level. Therefore, metabolic processes are disturbed in the cells of helminths, which ultimately leads to their death.

Pharmacokinetics:

When taking the drug orally, oxfendazole reaches its maximum concentration in the blood plasma in 6 hours, and oxyclozanide in 24 hours. Active substances and their metabolites are excreted from the body with urine and feces.

display:

It is used for deworming of cattle, sheep, goats in case of the following diseases: helminthosis of the gastrointestinal system Haemonchus contortus, Ostertagia ostertagi, Trichostrongylus, Nematodirus spp., Cooperia spp., Oesophagostomum spp., Trichuris spp. Dictyocaulus spp., Moniezia spp.
Liver trematode: Fasciola hepatica, Fasciola gigantica. The combination of two broad-spectrum anthelmintic substances included in the preparation ensures complete deworming of the target species.

Method of administration and dosage:

The drug is given orally, individually.

Cattle, sheep, goats - in case of fasciolosis, dicroceliosis, paramphistomatosis - 1 tablet per 50 kg of live weight. In the case of cestodes, 1 tablet per 60 kg of live weight.

Before mass treatment, preliminary testing of the drug is carried out in small groups of animals of each species. In case of complications, the use of the drug should be stopped for the given species.

Side effects:

Side effects and complications do not appear when using "Daxofen 900" according to the instructions.

Diarrhea, frequent defecation and urination may develop in case of overdose. Hypotension, which will pass 1-2 hours after stopping the drug.

Contraindications:

The drug is not used in animals with liver failure, in the first trimester of pregnancy and one month before parturition.

When individual sensitivity of the animal to the active components of the drug increases and/or allergic reactions occur, its use is stopped.

Waiting period:

Meat - 14 days

Milk - 4 days

Special instructions (safety measures):

When working with "Daxofen 900", the general rules of personal hygiene and safety, which are considered when working with veterinary drugs, should be followed.

Release form:

Tablet N100 placed in a vial of polymer material

Storage conditions:

Store in a dry place, protected from light, out of reach of children, at room temperature.

Expiry date:

3 years.

Country of manufacture:

Georgia

Production company:

Ltd. "dispute"

St. Tbilisi, Khandzteli St. No. 10.