Albendazole 360
Davat, Georgia
Anthelmintic drug for oral use
Trade name:
ALBENDAZOLE 360 ALBENDAZOLE 360
Generic (international non-patented) name:
Albendazole
Drug form:
1500 mg oral tablet
Description:
Gray or white, round, 16 mm diameter tablets with a flat surface, without a film, with a dividing groove on one side, and the manufacturer's mark on the other side.
Composition:
One tablet contains the active substance: Albendazole 360 mg
Pharmacological group:
an anthelmintic agent.
ATC vet code: QP52AC11 - Albendazole
Pharmacological action:
Albendazole is a derivative of benzimidazole carbamate, characterized by a wide spectrum of activity. It is active against adult and young nematodes, cestodes, as well as trematodes, has an ovicidal effect, which prevents contamination of pastures and stalls. Albendazole disrupts the activity of the microtubular system of intestinal canal cells of helminths; It inhibits the polymerization of microchannels, the process of glucose transport is disrupted by disintegration of microchannels, which causes a functional disruption of the microtubular apparatus in the body of helminths, as a result of which they die and are expelled from the body. In case of intestinal helminthiasis, albendazole is effective in a single dose, its bioavailability increases after eating.
Pharmacokinetics:
When taken orally, albendazole is better absorbed than other benzimidazoles and is distributed in all organs. The main metabolites albendazole sulfoxide and albendazole sulfone reach their maximum concentration in the blood plasma within 20 hours after entering the body. The highest concentration of metabolites (sulfoxide or sulfone) is observed in the liver, kidneys, muscles and remains in these organs for 13 days. About 47% of the dose is excreted with urine, the rest with the gallbladder in the form of metabolites.
display:
It is used for the deworming of agricultural animals and birds in case of the following diseases: gastrointestinal helminthosis (haemoncosis, bunostomosis, esophagostomosis, nematodirosis, ostertagiosis, kabertiosis, cooperiosis, strongyloidosis, hyostrogillosis, paraascaridosis, trichocephalosis, toxo Carosis, toxocaridosis, uncinariasis, ascaridosis, heterakidosis ), pulmonary helminthoses (dictiocaulosis, protostrongyllosis, mülleriosis, neostrongyllosis, cystocaulosis, metastrongyllosis), cestodoses (moniesiosis, avitelinosis, thysaniosis), trematodoses (fasciolosis, dicroceliosis, paramphistomatosis).
Side effects:
Side effects and complications do not appear when using "Albendazole 360" according to the instructions.
Symptoms of overdose have not been detected in animals.
Method of administration and dosage:
The drug is given without prior fasting diet, orally, individually or by group method. Cattle, sheep, goats, horses, donkeys, pigs are given the drug once with food. Birds (chicken, turkey, duck, goose) are mixed in food twice.
When using the drug by an individual method
Cattle - for nematodes and cestodoses - 1 tablet per 50 kg of live weight. In the case of trematodes, the dose is doubled to 1 tablet per 25 kg of live weight.
Sheep, goats - for nematodes, cestodes - 1 tablet per 70 kg of live weight. For trematodes, the dose is doubled to 1 tablet per 35 kg of live weight.
Horse, donkey - paraascariodosis, oxyurosis, strongylatosis and strongyloidosis 1 tablet per 50 kg of live weight
Pig - ascaridosis, metastrongylosis, esophagostomosis, trichocephalosis, strongyloidosis 1 tablet per 35 kg of live weight by mixing in feed.
Poultry (chicken, turkey, duck, goose) - in ascaridosis, heterokidosis, the drug is prescribed in groups, mixed with food, for two consecutive days. In the morning, 1 tablet per 25 kg of live weight.
Before mass treatment, preliminary testing of the drug is carried out in small groups of animals of each species. In case of complications, the use of the drug should be stopped for the given species.
Repeated treatment is allowed after 14 days.
Contraindications:
The drug is not used in weak, weakened animals. In acute fasciolosis, in cattle in the first third of age, in pigs and sheep in the first half of age.
When individual sensitivity of the animal to the active components of the drug increases and/or allergic reactions occur, its use is stopped.
Waiting period:
Meat - 12 days
Milk - 4 days
Special instructions (safety measures):
When working with albendazole, the general rules of personal hygiene and safety, which are considered when working with veterinary drugs, should be observed.
Interaction with other drugs:
With simultaneous use with dexamethasone, praziquantel, it is possible to increase the concentration of albendazole sulfoxide in the blood plasma.
Release form:
Tablet No. 10 on a blister, blister No. 10 in a cardboard box
Storage conditions:
Store in a dry, cool, light-protected place at room temperature.
Expiry date:
3 years.
Country of manufacture:
Georgia
Production company:
Ltd. "dispute"
St. Tbilisi, Khandzteli St. No. 10.